Cannabis (i.e., medical marijuana) has been proved in numerous studies to be a viable alternative to prescription painkillers. However, the intoxicating properties of marijuana deter many individuals from using it. Cannabidiol (CBD), a non-intoxicating component found in cannabis, is used to treat a variety of disease conditions, including pain relief. We noticed that some of the top CBD oils might help with pain management treatment.
CBD, on the other hand, is not FDA-approved for pain treatment. As a result, the items and claims mentioned in this article are not verified by the FDA. As a consequence, they should not be used to assess, treat, cure, or prevent any disease or medical condition.
Even before the FDA’s approval, CBD has already received a lot of media attention. You’ve undoubtedly seen prominent news sources cover CBD or hear about it being suggested by high-profile social figures for a variety of pain alleviation.
How Does CBD Work?
Cannabis has been used to treat pain and inflammation since time immemorial. Cannabis was reportedly used as a medicine in ancient China, when Emperor Shen-Nung included it in the Chinese pharmacopeia with other therapeutic drugs. To relieve pain and discomfort, leaves were applied as a poultice to boost recovery.
Despite its widespread use, scientists have only recently begun to understand the mechanisms by which cannabis helps with pain. Since 1992, researchers have identified the endocannabinoid system and CBD and other phytocannabinoids have been in the limelight of modern medicine.
The endocannabinoid system, one of the body’s most important neurochemical systems, is made up of numerous components. It connects with the endocannabinoid system, a network of hormones and receptors that aids in a variety of basic bodily processes. Cannabis plant chemicals are comparable to our natural hormones produced via the endocannabinoid system.
Cannabidiol (CBD) and other cannabinoids interact with the endocannabinoid system and exert a variety of effects via their interaction with the endocannabinoid system, including:
- Immune function
- Sensory perception (including pain)
- Reproductive health
- Nerve function
How Can CBD Reduce Pain Transmission?
What does this information tell us? What do you mean by this, exactly? What is the significance of this discovery? When we harm ourselves, neighboring cells release chemicals that set off a chain reaction of inflammation and sensation production, resulting in pain transmission.
The sensation of pain is then transferred to the spinal cord via a network of nerves that cover the entire body. The pain signal is sent into the spine, where it is received by a checkpoint (opioid and vanilloid receptors) intended to restrict information transmission to the brain. This serves as a border control mechanism. Security personnel ensure that you are authorized to enter and what you can bring with you in.
The following are some of the reasons why persons with chronic pain may feel as though they’re being ignored by society. These hurdles can limit how much pain information makes it to the brain. If more pain signals were permitted to pass, the brain would perceive greater discomfort. Pain-relieving medications act by activating opioid receptors, which are key traffic check points for transporting pain data to the mind.
CBD works by binding to these vanilloid receptors, which are found in various locations of the body. CBD binds to different types of receptors known as the vanilloid receptors. Inflammation-related pain sensations such as those caused by heat or irritation are controlled using these vanilloid receptors. CBD has been found to modulate this vanilloid receptor, reducing inflammation-related pain signals such as arthritic discomfort, muscular damage, and infection symptoms.
CBD has other ways it can limit pain transmission as well:
- CBD has anti-inflammatory effects, which may help with a variety of health issues.
- CBD functions as an antioxidant, aiding the body’s resistance to and recovery from injury.
- CBD reduces muscular spasms and tightness, resulting in less pain.
There is still a lot more research to be done in order to really understand how CBD and other active cannabinoids can help with pain. Every year, dozens of new study papers are published in an attempt to build a clear understanding of how CBD works, what the drug’s benefits are, and where its limits exist.
What Do the Studies Say?
The effect of CBD on pain is increasingly being investigated. In a study featured in the European Journal of Pain, researchers examined the influence of transdermal CBD on rats with induced arthritis. For four days, researchers applied CBD gels to rat arthritic painful joints at four different dosages (0.6, 3.1, 6.2, and 62.3mg) per day (n = 8).
Researchers discovered that CBD gel reduced joint edema by a staggering 100 percent, with the 62.3mg dose being no more effective than the 6.2mg one.
Meanwhile, a research published in Frontiers in Immunology last year looked at CBD’s anti-inflammatory benefits on mice. CBD administration resulted in decreased inflammatory markers after ten days in mice. They used a mouse model of encephalitis to mimic the symptoms of multiple sclerosis on a person’s body to develop the mouse model of MS.
In scientific study, cannabidiol made pain seem less terrible, but it didn’t decrease experimental pain intensity.
In 2021, scientists at Syracuse University conducted a further study that demonstrated CBD’s pain-relieving abilities. It’s significant because it was the first clinical pain trial to look at CBD’s effect on individuals. Cannabidiol reduced experimental pain unpleasantness but did not reduce experimental pain intensity, according to the findings.
According to a research, CBD was found to be more effective than a placebo in decreasing pain symptoms. This is undoubtedly an important first step toward acceptance of CBD as an pain-relieving option.
Using CBD Oil for Pain
CBD oil is typically taken by placing it under the tongue and holding it there for up to 60 seconds before swallowing. This technique ensures that a portion of the CBD enters your circulation through your mouth.
When used topically, CBD oil for pain relief may be a more effective option. Putting it on the painful site might be a better option than applying it directly to the afflicted area. A topical solution of cannabidiol appears to absorb more effectively than CBD oil. According to those who massage CBD on their skin frequently, the therapy is more efficient.
If you’re using CBD for the first time, only apply it to a tiny area of skin. You must exercise caution not to achieve an undesirable reaction. Increase the amount you use until you reach the “minimum therapeutic dose,” which is a term that refers to a situation in which you employ the smallest quantity feasible in order to accomplish your goal.
Benefits of CBD Oil – Anecdotal Evidence
CBD oil, despite the fact that it is not yet recognized by the FDA as a pain medication, has a wide range of benefits for millions of people all around the world. Here are a few excerpts from reader-submitted testimonies regarding CBD’s influence on everyday discomfort:
Best CBD Oil for Pain: Side Effects
Despite the fact that hemp oil is as safe as CBD, there are certain adverse effects linked with it. When compared to the severe side effects of prescription painkillers and other narcotic pain relievers, these minor drawbacks are insignificant.
The most reliable source for reporting CBD’s drawbacks is the Epidiolex (a FDA-approved cannabidiol drug used to treat two rare types of epilepsy) clinical trials. According to the research, cannabidiol users may experience the following adverse effects:
- Decreased appetite
- Transaminase elevations
- Fatigue, malaise, and asthenia
- Insomnia, sleep disorder, and poor-quality sleep
CBD has also been linked to the interaction with a variety of other medications, including over-the-counter and prescription medication. Furthermore, it’s possible that CBD use may have an impact on liver health, but this has yet to be investigated. CBD is also a known activator of enzymes and drug metabolizing. As a result, before using CBD in addition to other medicines, it is important to discuss this with your doctor.
Now that you know more about how CBD oil for pain works, let’s take a look at the top CBD oil brands and their product lines! Do you want to read or see a comprehensive explanation of our top CBD oil picks? Rather than that, here is a quick rundown of our video CBD oil countdown.